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[answered] Can any of you help me with this assignment please!?


Can any of you help me with this assignment please!?

Pick an enzyme of your choosing (except carbonic anhydrase) whose structure and mechanism is known. Write a brief summary about the physiological relevance of the enzyme, its structure, any diseases it is involved in, and evidence that supports its mechanism.

Project Requirements: (20 pts each)

  • 250+ word introduction to the enzyme. Include physiological relevance, what biochemical pathway it is a part of, and any diseases it is involved in
  • SwissPDB ribbon diagram of the overall structure of the enzyme: Include a figure legend that describes its structure.
  • Reaction mechanism: A picture or drawing of the mechanism by which this enzyme works, including which amino acid residues are involved in the mechanism. Include a figure legend highlighting key parts of the mechanism AND evidence for the mechanism taking place the way it does.
  • SwissPDB screenshot of the active site residues in the enzyme that are involved in the mechanism. The residues should be labeled and their role in the mechanism should be described in the figure legend.
  • Three references, one which must be primary literature

 


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